Is It Possible to Reverse Type 2 Diabetes?

Is It Possible to Reverse Type 2 Diabetes?

Can Diabetes Be Reversed?

A few weeks ago, I had a patient come to see me. They had had type 2 diabetes for quite a few years.  Spurred by a trip to the emergency room for circumstances unrelated to their diabetes, they were trying to take control of all aspects of their health – including their diabetes.

“Ma’am – I want to reverse my diabetes. What can I do?”

“Well, it isn’t always that easy,” I explained to the patient.

So I went on to explain to him the latest research.

Is Prediabetes Curable?

Well, it’s certainly true that if you have been diagnosed with borderline diabetes (also sometimes known as prediabetes) there are steps you can take to cut down on the likelihood of developing the full-blown disease.

Prediabetes is when blood glucose levels are higher than normal, but not yet high enough to be classed as diabetes. It’s a kind of “gray area” between normal blood sugar and diabetic levels.

In the UK, around 7 million people are thought to have prediabetes. In 2012, 86 million Americans aged 20 and older were diagnosed with prediabetes; this figure was up from 79 million in 2010.

The good news is that cases of prediabetes identified early on can be reversed, preventing them from progressing into full-blown type 2 diabetes.

The two main things people with borderline diabetes can do to lower the chance of developing type 2 diabetes is to change their diet and lifestyle. By making these changes, blood sugar levels may be returned to normal.


A consultation with a doctor and possibly a specialist nutritionist would be the first step — they will be able to show you where you can make changes which may well impact your overall health for the better.

Is Type 2 Diabetes Reversible?

Have you ever heard of β-cells? These types of cells are specific to the pancreas and are responsible for insulin production.

  • If you have type 1 diabetes, they completely fail – meaning that they ultimately stop producing insulin completely.
  • If you have type 2 diabetes, your β-cells are not working appropriately for some reason, and there may be a lack of insulin, or insulin resistance – or both.

The consensus at one point in time was that type 2 diabetes was irreversible due to β-cell loss. Most researchers believed that at diagnosis, there was a significant loss of β-cells, although the amount varied from researcher to researcher.

In addition, “The impaired insulin secretion found in T2D could be due to a decline in the cellular secretory rate (that is, in individual β-cell function), or to a decrease in β-cell mass (the product of β-cell size and number), or both.”

However, current research is changing our line of thinking…

A small-scale study performed in England researched the effect of a liquid diet on people with type 2 diabetes – some of those living with type 2 diabetes for up to 23 years. At the conclusion of the study, about half of the participants had achieved remission of their diabetes.

Can Type 2 Diabetes be Reversed Naturally?

Dr. Roy Taylor of Newcastle University in England, who authored the study, states, “This is a radical change in our understanding of Type 2 diabetes. If we can get across the message that ‘yes, this is a reversible disease — that you will have no more diabetes medications, no more sitting in doctors’ rooms, no more excess health charges’ — that is enormously motivating.”

At the conclusion of the study, the researchers followed up with the study participants. As discussed, the participants had followed a low-calorie liquid diet for the duration of the study. The diet specifically contained 600 to 700 calories per day, with three milkshakes and half a pound of non-starchy vegetables. In addition, participants stopped taking all diabetic medications.

At the conclusion of the study, the participants resumed a normal diet. The participants who had achieved remission were still in remission, six months later.

Dr. Taylor states that he isn’t sure why the low calorie, liquid diet works, but he hypothesizes that it “may be related to how the body stores fat. Excess fat in the liver can spill into the pancreas, inhibiting insulin secretion and the liver’s response to insulin, resulting in insulin resistance and diabetes.”

Can Diabetes Be Reversed by Diet?

The particular research study that we’re referencing in this article utilized a low-calorie, liquid diet. The study participants drank “low-calorie milkshakes” for the duration of the study.

One hypothesis is that a very-low-calorie-diet may allow the body to utilize fat that is stored in the liver. This may cause the body to use the fat that is stored in the pancreas as well. Using the fat from these areas could then “wake up” the insulin-secreting capabilities of the β-cells of the pancreas. Again, this is just a hypothesis.

But is this type of diet sustainable?  Dr. George King, the chief scientific officer at Joslin Diabetes Center and professor at Harvard Medical School isn’t quite sure. He states that that the diet is “definitely doable” but questions whether the weight loss is sustainable – meaning, is the reversal of type 2 diabetes reasonable on a long-term basis?

However, Dr. King goes on to point out that even a short-term reversal of type 2 diabetes can reduce serious complications of type 2 diabetes, such as heart disease, strokes, diabetic neuropathy, and diabetic neuropathy.

The Bottom Line…

Although the research is extremely exciting, this diet is extreme. Further research needs to be conducted to quantify this research. Do not attempt to follow a very-low-calorie-diet without advice from your physician, and do not stop taking any insulin or other diabetes medications without the advice of your physician – especially if you have type 1 diabetes.


New York Times (Hope for Reversing Type 2 Diabetes)

US National Library of Medicine National Institutes of Health (Q&A: Insulin Secretion and Type 2 Diabetes: Why Do β-cells Fail?)

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